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Title :Direct Pulp Capping Effect with Experimentally Developed Adhesive Resin Systems Containing Reparative Dentin Promoting Agents on Rat Pulp -Mixed Amounts of Additives and Their Effect on Wound Healing-
Authors :Taira, Yoshihisa
Shinkai, Koichi
Suzuki, Masaya
Kato, Chikage
Katoh, Yoshiroh
Publisher :Springer
Issue Date :Jul-2011
Journal Title :Odontology : Official journal of the Society of the Nippon Dental University
Volume :99
Issue :2
Start Page :135
End Page :147
ISSN :1618-1247
Abstract :This study examined the wound healing process of exposed rat pulp when treated with experimental adhesive resin systems. The experimental direct pulp capping adhesive resin systems were composed of primer-I, primer-II and an experimental bonding agent. Primer-I was Clearfil SE Bond (CSE) primer containing 1.0 or 5.0wt% CaCl2, and primer-II was CSE primer containing 0.1, 1.0 or 5.0wt% compound of equal mole of pA and pB with synthetic peptides derived from dentin-matrix-protein 1 (DMP1). Primer-I containing 1.0wt% and 5.0wt% CaCl2 were assigned to the experimental groups 1 to 3, and 4 to 6, respectively. Primer-II containing 0.1, 1.0 or 5.0wt% compound of pA and pB were assigned to the experimental groups 1 and 4, 2 and 5, and 3 and 6, respectively. In all experimental groups, CSE bond containing 10wt% hydroxyapatite powder was used as the experimental bonding agent. The positive control teeth were capped with calcium hydroxide preparation (Dycal), and the negative control teeth were capped with CSE. The specimens were alternately stained with Mayer's H&E and the enhanced polymer one-step staining method. Experimental groups 1, 4, 5 and 6 showed a higher level of reparative dentin formation compared to the negative control 14 days postoperatively. At 28 days postoperatively, all experimental groups showed the formation of extensive reparative dentin, and experimental groups 4, 5 and 6 demonstrated similar dentin bridge formation as that of the positive control. How quickly reparative dentin formation occurs might depend on the concentration of CaCl2 and pA and pB in the experimental primer.
Keywords :Adhesive resin
Direct pulp capping
Calcium chloride
Dentin matrix protein 1
Hydroxyapatite
Type Local :Journal Article
Language :eng
URI :http://hdl.handle.net/10623/31739
Appears in Collections:10 査読済論文 = Postprint

Please use this identifier to cite or link to this item: http://hdl.handle.net/10623/31739

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